generally a bigger intercooler means more volume to fill up and thus more laggy as mentioned above but also depends on which big intercooler you're looking at. not all intercoolers are made the same, the frc items in particular, have very few additional internal fins within the tubes so its fin surface area to conduct heat from the compressed air inside is much less compared to good japanese intercoolers. if you get a large lorry intercooler then the lag will be very bad due to the compound effect of a huge volume to fill and low flow efficiencies. the pipings(length and diameter) also has a role to pllay as mentioned above. generally speaking, get a moderately sized intercooler and make sure it is front mount for maximum cooling. also pay as expensive an intercooler as you can afford which has very low pressure drop. so if you're thinking of replacing your standard gsr item with an frc supra sized ic, i would strongly discourage. but going from a gsr to say a good hks or even apexi evo sized ic, you will lose some response, but ultimately when you go for higher boost over sustained WOT conditions, you will start seeing gains.