sound quality will differ with regards to power from the amp la, like i said earlier, if the 8 ohm tweeter power rating is 50W rms, u will need a 100W rms car amplifier, since car amps are rated at 4ohm.
the other problem will be when u use passive crossovers that was not meant for 8ohm speakers. since car speakers are usually rated at 4ohm, so the capacitor and coils in the passive xover will give different high pass and lowpass frequencies, when they are connected to 8ohm. so in this way the SQ will usually be not as good.